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what is HCG?

March 15, 2022

What is HCG? Human chorionic gonadotropin (HCG) is a glycoprotein secreted by trophoblast cells of the placenta, and it is composed of alpha and beta dimerized glycoproteins. A glycoprotein hormone with a molecular weight of 36700, the α subunit is basically similar to FSH (follicle stimulating hormone), LH (luteinizing hormone) and TSH (thyroid stimulating hormone) secreted by the pituitary gland, so they can cross-react with each other, while the β subunit The structures of the bases vary. In mature women, after the fertilized egg moves into the uterine cavity and implants, an embryo is formed. During the process of development and growth into a fetus, the placental syncytiotrophoblast cells produce a large amount of HCG, which can be excreted into the urine through the maternal blood circulation. At 1 to 2.5 weeks of gestation, HCG levels in serum and urine can rapidly increase, peak at the 8th week of pregnancy, and then drop to moderate levels at the 4th month of pregnancy, and remain at the end of pregnancy. Currently commonly used detection methods are: latex set inhibition test and hemagglutination inhibition test; radioimmunoassay (RIA); enzyme-linked immunosorbent assay (ELISA); monoclonal antibody colloidal gold test. clinical significance The examination of HCG is of great significance for the diagnosis of early pregnancy, and has a certain value in the diagnosis, identification and observation of disease course of pregnancy-related diseases, trophoblastic tumors and other diseases. 1. Increased seen in: early pregnancy, hydatidiform mole, malignant hydatidiform mole, chorioepithelial cell carcinoma, seminoma, teratoma, ectopic HCG-secreting tumors (such as gastric cancer, pancreatic cancer, lung cancer, colon cancer, liver cancer, ovary cancer, carcinoid of the digestive system, etc.). 2. Reduced in: miscarriage, etc. HCG normal reference range ml; >150IU/ml means possible pregnancy. Our company mainly engaged in export of products including, without limitation, pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acids, Veterinary , API Medical, Bodybuilding Peptides, sarms ,steriods,hormone, Plant Extract, food additives, Feed Additives , cosmetic raw materials , tb500,CBD Oil and provide natural and well-qualified raw materials to the companies being engaged in pharmaceutical,health product, nutritional product, cosmetic. with very strong strength in R&D, production, sale and other aspects in the national plant extract industry.

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